News

July 17,2026

Office Closure for the Japanese Summer Holiday

June 10, 2026

New User’s Voice released

The article “‘It couldn’t have been possible without the CELL HANDLER™’—Automation That Enables the Isolation of Clones in a 3D Culture” features an interview with Yuichiro Miyaoka.

April 16, 2026

Article in Nature

Our advertisement feature ' Stepping up to the plate for cancer research' was published as part of the special issue 'Nature Index: Cancer' in the international multidisciplinary scientific journal ‘Nature’.

• https://www.nature.com/articles/d42473-025-00450-x

March 10, 2026

Publication

• Yasmine Abouleila, Gakuro Harada, Sylvia F. Boj, et al. “Accelerating personalized medicine: miniaturized patient-derived organoid drug screening for predicting cancer treatment responses and beyond” npj Biomedical Innovations 3, Article number: 16 (2026)
• Satoshi Ikeo, Toshio Suzuki, Saburo Ito, Yuki Yamamoto, Shoji Takeuchi, et al. “Dynamic in vitro platform for mechanical profiling of human pulmonary aciniform organoids via intraluminal access” Biomaterials, 26 February 2026, 124094

March 9, 2026

New User’s Voice released

The article “Automation Holds the Key to Addressing Unmet Medical Needs in Respiratory Diseases,” features an interview with Yuki Yamamoto.

February 11, 2026

New applications released

• Automated Spheroid Picking and Transfer from AggreWell™ Plate Using CELL HANDLER™2
• Automated Spheroid Picking and Transfer from EZSPHERE^® Plate Using CELL HANDLER™2
• Accurate Automated Cell Transfer with Yamaha Precision Tip™ in Various Applications

February 6, 2026

New applications released

• High-Accuracy Cell Detection Combining the CELL HANDLER™2 and the AI Image Recognition Model
• High-Accuracy High-Efficiency Spheroid Transfer Using the CELL HANDLER™

December 4, 2025

News Release

Yamaha Motor Launches Strategic Partnership with Nikon Instruments , USA - Creating Synergies Between Both Companies in Advanced Technologies and Support Services for Drug Discovery -

August 7, 2025

News Release

Yamaha Motor Begins Joint Research Using Cell Handling Technology with a national research institute - Advancing Next-Generation Automated Experimentation to Promote DX and AX in Research -

August 7, 2025

Conference Presentations

A study using CELL HANDLER™ was presented at SLAS2025 International Conference & Exhibition:

Miniaturizing patient-derived organoid screening assays for predictive drug testing

June 16, 2025

Publication

Gou Takahashi, Minato Maeda, Kayoko Shinozaki, Yuichiro Miyaoka , et al. “High-throughput robotic isolation of human iPS cell clones reveals frequent homozygous induction of identical genetic manipulations by CRISPR-Cas9”Stem Cell Research & Therapy volume 16, 2025

June 16, 2025

News Release

Yamaha Motor Makes First International Delivery of the CELL HANDLER™ 2 to U.S. Research Institute— Set for use in cutting-edge cancer research at Fred Hutch Cancer Center —

June 16, 2025

Article in Nature

An article about the CELL HANDLER™ was published in Nature. HiLung and Hub Organoids talk about how the CELL HANDLER™ helps their research.

• Expanding the reach of organoid research

November 14, 2024

Conference Presentations

Yamaha Motor Co., Ltd. will introduce the CELL HANDLER™2 in March 2025!

October 7, 2024

Conference Presentations

A study using CELL HANDLER was presented at the 9th Annual Meeting of The Japanese Society for Genome Editing.

• Profiling Genome Editing Outcomes in Individual Human iPS Cells and Cultured Cells

March 7, 2024

New applications released

• Development of a process to sort high antibody-producing cells using the CELL HANDLER™

August 2, 2023

Publication
Fujimura T, Enomoto Y, Katsura H, et al.
“Identifying a Lung Stem Cell Subpopulation by Combining Single-Cell Morphometrics, Organoid Culture, and Transcriptomics” Stem Cells,2023 July

October 22, 2021

New applications released

• Automated placement of varied sized spheroids in Organ on a Chip, Mimetas OrganoPlate^® Graft by CELL HANDLER™

June 21, 2021

Publication
Higa A, Takahashi N, Hiyama G, et al.
“High-Throughput In Vitro Assay using Patient-Derived Tumor Organoids” J. Vis. Exp. 2021 Jun;(172)

October 22, 2021

New applications released

• Automated iPS cell sorting by using CELL HANDLER™ (CiRA Foundation)

June 21, 2021

New applications released

• Advanced approach for 3D-cell phenotypic assay

April 9, 2021

Publication
Takahashi N, Higa A, Hiyama G, et al.
“Construction of in vitro patient‑derived tumor models to evaluate anticancer agents and cancer immunotherapy” Oncol Lett. 2021 May;21(5):406

May 23, 2019

Kondo J, Ekawa T, Endo H, et al.
High-throughput screening in colorectal cancer tissue-originated spheroids. Cancer Sci. 2019;110:345‐355. PubMed

July 25, 2018

YAMAHA CELL HANDLER™ earned the New Product Awardat the 2018 SLAS* Europe Conference and Exhibition.
*Society for Laboratory Automation and Screening